From version 1901, Dolby audio mixing enhancement effects (e.g. Dolby ProLogic IIx, Dolby Virtual Speaker, Dolby Headphone.) are no longer supported on newer PowerDVD 19 versions.
If you'd still like to downmix or upmix with virtual sound effects, you are highly recommended to use the TrueTheater Surround feature.
For video files or movie discs (DVD/Blu-ray) that are encoded with Dolby audio, they are still compatible with PowerDVD 19.